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401 Within the hypoxic and nutrient-deprived TME, TAMs undergo profound metabolic reprogramming, including enhanced oxidative metabolism, increased arginase-1 activity, and lipid accumulation, which collectively drive polarization toward an M2-like phenotype characterized by the secretion of IL-10 and TGF-β

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“So, eating a sufficient amount of lean protein is important.” These healthier proteins promote a more balanced diet, while also helping your liver do its important work — which is a win-win